The D.O.C. was thought of as one of rap's most promising new voices because of his association with N.W.A. and was at the height of his career after penning the lyrics and contributing vocals to Eazy E's debut and the group's revolutionary album, Straight Outta Compton.

In 1989, The D.O.C. then released his Dr. Dre produced debut album No One Can Do It Better. Dre's production was similar to his production work for N.W.A at the time, but he also included one rap/rock-song and a reggae-influenced track. At a time when virtually every well known California rapper was releasing gangsta rap albums, The D.O.C. released an LP with lyrics that more closely resembled the styling of East Coast lyricists. The D.O.C. also wrote many lyrics and appeared on skits for NWA, particularly on the album Efil4zaggin. He went on to introduce Dr. Dre to Suge Knight, and he helped mold the career of Snoop Dogg.

Not long after his debut album was released, his vocal cords were severed in a car accident, which would prove to be an insurmountable obstacle for his continued rap career. However, The D.O.C. remained important to Dr. Dre. He used his talents as one of the writers for Dr. Dre's groundbreaking album The Chronic, contributing to the tracks "Lil' Ghetto Boy," "A Nigga Witta Gun," and "Bitches Ain't Shit." In fact, the liner notes to The Chronic say "I wantto give a special shout out to The D.O.C. for talking me into doin' this album." The D.O.C. also worked on Snoop Dogg's debut album Doggystyle.



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